| QB | QB5Season rank QB5 through week 1, inside the league's starting line: Jalen Hurts 24.28 | QB11Season rank QB11 through week 1, outside the league's starting line: Bo Nix 8.84 |
| RB | RB4Season rank RB4 through week 1, inside the league's starting line: Christian McCaffrey 18.70 | RB25Season rank RB25 through week 1, startable in a flex slot: Jahmyr Gibbs 10.00 |
| RB | RB23Season rank RB23 through week 1, startable in a flex slot: Ashton Jeanty 11.00 | RB3Season rank RB3 through week 1, inside the league's starting line: Javonte Williams 19.40 |
| WR | WR9Season rank WR9 through week 1, inside the league's starting line: Marvin Harrison Jr. 15.60 | WR29Season rank WR29 through week 1, inside the league's starting line: Brian Thomas Jr. 8.50 |
| WR | WR41Season rank WR41 through week 1, startable in a flex slot: Jameson Williams 4.60 | WR12Season rank WR12 through week 1, inside the league's starting line: Jaxon Smith-Njigba 14.90 |
| WR | WR43Season rank WR43 through week 1, startable in a flex slot: George Pickens 4.50 | WR26Season rank WR26 through week 1, inside the league's starting line: Jerry Jeudy 9.10 |
| TE | TE6Season rank TE6 through week 1, inside the league's starting line: Kyle Pitts Sr. 9.40 | TE5Season rank TE5 through week 1, inside the league's starting line: George Kittle 10.50 |
| FLEX | WR21Season rank WR21 through week 1, inside the league's starting line: DK Metcalf 10.30 | RB18Season rank RB18 through week 1, inside the league's starting line: Alvin Kamara 12.70 |
| FLEX | WR2Season rank WR2 through week 1, inside the league's starting line: Emeka Egbuka 21.60 | WR27Season rank WR27 through week 1, inside the league's starting line: Chris Olave 8.90 |
| K | K1Season rank K1 through week 1, No. 1 at the position: Ka'imi Fairbairn 14.00 | K3Season rank K3 through week 1, inside the league's starting line: Brandon Aubrey 11.00 |
| DEF | DEF5Season rank DEF5 through week 1, inside the league's starting line: MIN Defense 6.00 | DEF4Season rank DEF4 through week 1, inside the league's starting line: HOU Defense 7.00 |