| QB | QB7Season rank QB7 through week 1, inside the league's starting line: Jayden Daniels 22.12 | QB6Season rank QB6 through week 1, inside the league's starting line: Kyler Murray 22.32 |
| RB | RB1Season rank RB1 through week 1, No. 1 at the position: Derrick Henry 28.70 | RB21Season rank RB21 through week 1, startable in a flex slot: Chase Brown 12.10 |
| RB | RB22Season rank RB22 through week 1, startable in a flex slot: Jonathan Taylor 11.30 | RB8Season rank RB8 through week 1, inside the league's starting line: Chuba Hubbard 16.40 |
| WR | WR32Season rank WR32 through week 1, startable in a flex slot: Mike Evans 7.60 | WR47Season rank WR47 through week 1, startable in a flex slot: Ja'Marr Chase 3.60 |
| WR | WR48Season rank WR48 through week 1, startable in a flex slot: DeVonta Smith 3.10 | WR56Season rank WR56 through week 1, outside the league's starting line: A.J. Brown 1.30 |
| WR | WR40Season rank WR40 through week 1, startable in a flex slot: Calvin Ridley 4.70 | WR37Season rank WR37 through week 1, startable in a flex slot: Tyreek Hill 6.00 |
| TE | TE2Season rank TE2 through week 1, inside the league's starting line: Travis Kelce 11.70 | TE3Season rank TE3 through week 1, inside the league's starting line: Tyler Warren 11.40 |
| FLEX | RB32Season rank RB32 through week 1, startable in a flex slot: Austin Ekeler 7.20 | RB31Season rank RB31 through week 1, startable in a flex slot: Tony Pollard 7.40 |
| FLEX | RB37Season rank RB37 through week 1, startable in a flex slot: Tyrone Tracy Jr. 4.50 | WR25Season rank WR25 through week 1, inside the league's starting line: Tetairoa McMillan 9.30 |
| K | K7Season rank K7 through week 1, inside the league's starting line: Jake Elliott 8.00 | K6Season rank K6 through week 1, inside the league's starting line: Wil Lutz 8.00 |
| DEF | DEF2Season rank DEF2 through week 1, inside the league's starting line: LAR Defense 12.00 | DEF6Season rank DEF6 through week 1, inside the league's starting line: ARI Defense 5.00 |