| QB | QB10Season rank QB10 through week 16, inside the league's starting line: Matthew Stafford 36.88 | QB9Season rank QB9 through week 16, inside the league's starting line: Justin Herbert 34.20 |
| RB | RB8Season rank RB8 through week 16, inside the league's starting line: Kyren Williams 10.00 | RB3Season rank RB3 through week 16, inside the league's starting line: Jahmyr Gibbs 17.80 |
| RB | RB15Season rank RB15 through week 16, inside the league's starting line: D'Andre Swift 8.00 | RB13Season rank RB13 through week 16, inside the league's starting line: Chase Brown 30.90 |
| WR | WR2Season rank WR2 through week 16, inside the league's starting line: Puka Nacua 40.50 | WR11Season rank WR11 through week 16, inside the league's starting line: A.J. Brown 14.00 |
| WR | WR37Season rank WR37 through week 16, startable in a flex slot: DJ Moore 19.40 | WR12Season rank WR12 through week 16, inside the league's starting line: Tetairoa McMillan 16.30 |
| WR | WR32Season rank WR32 through week 16, startable in a flex slot: Jauan Jennings 15.60 | WR5Season rank WR5 through week 16, inside the league's starting line: Ja'Marr Chase 15.40 |
| TE | TE1Season rank TE1 through week 16, No. 1 at the position: Trey McBride 4.70 | TE4Season rank TE4 through week 16, inside the league's starting line: Tyler Warren 4.50 |
| FLEX | RB17Season rank RB17 through week 16, inside the league's starting line: Breece Hall 7.30 | RB43Season rank RB43 through week 16, outside the league's starting line: Tyler Allgeier 7.80 |
| FLEX | TE10Season rank TE10 through week 16, inside the league's starting line: Kyle Pitts Sr. 15.20 | RB20Season rank RB20 through week 16, inside the league's starting line: Quinshon Judkins 7.60 |
| K | K13Season rank K13 through week 16, outside the league's starting line: Cam Little 11.00 | K2Season rank K2 through week 16, inside the league's starting line: Cameron Dicker 10.00 |
| DEF | DEF2Season rank DEF2 through week 16, inside the league's starting line: DEN Defense 4.00 | DEF20Season rank DEF20 through week 16, outside the league's starting line: MIN Defense 11.00 |