| QB | QB17Season rank QB17 through week 16, outside the league's starting line: Trevor Lawrence 37.16 | QB8Season rank QB8 through week 16, inside the league's starting line: Drake Maye 27.70 |
| RB | RB7Season rank RB7 through week 16, inside the league's starting line: Travis Etienne Jr. 14.60 | RB11Season rank RB11 through week 16, inside the league's starting line: Derrick Henry 22.80 |
| RB | RB18Season rank RB18 through week 16, inside the league's starting line: Rico Dowdle 6.30 | RB2Season rank RB2 through week 16, inside the league's starting line: Jonathan Taylor 15.40 |
| WR | WR14Season rank WR14 through week 16, inside the league's starting line: Jaylen Waddle 9.70 | WR20Season rank WR20 through week 16, inside the league's starting line: DeVonta Smith 13.20 |
| WR | WR49Season rank WR49 through week 16, startable in a flex slot: Troy Franklin 8.60 | WR18Season rank WR18 through week 16, inside the league's starting line: Michael Pittman Jr. 5.20 |
| WR | WR30Season rank WR30 through week 16, inside the league's starting line: Khalil Shakir 5.40 | WR26Season rank WR26 through week 16, inside the league's starting line: Keenan Allen 6.90 |
| TE | TE23Season rank TE23 through week 16, startable in a flex slot: Mike Gesicki 11.00 | TE2Season rank TE2 through week 16, inside the league's starting line: Travis Kelce 1.10 |
| FLEX | WR23Season rank WR23 through week 16, inside the league's starting line: Stefon Diggs 18.30 | RB39Season rank RB39 through week 16, startable in a flex slot: Tyrone Tracy Jr. 8.80 |
| FLEX | RB23Season rank RB23 through week 16, startable in a flex slot: David Montgomery 1.40 | WR54Season rank WR54 through week 16, outside the league's starting line: Mike Evans 11.60 |
| K | K8Season rank K8 through week 16, inside the league's starting line: Ka'imi Fairbairn 16.00 | K5Season rank K5 through week 16, inside the league's starting line: Jake Elliott 1.00 |
| DEF | DEF4Season rank DEF4 through week 16, inside the league's starting line: BUF Defense 8.00 | DEF9Season rank DEF9 through week 16, inside the league's starting line: BAL Defense 9.00 |