| QB | QB14Season rank QB14 through week 2, outside the league's starting line: Justin Fields 3.98 | QB6Season rank QB6 through week 2, inside the league's starting line: Jayden Daniels 23.70 |
| RB | RB14Season rank RB14 through week 2, inside the league's starting line: Jahmyr Gibbs 17.90 | RB10Season rank RB10 through week 2, inside the league's starting line: Derrick Henry 2.30 |
| RB | RB2Season rank RB2 through week 2, inside the league's starting line: Javonte Williams 22.00 | RB3Season rank RB3 through week 2, inside the league's starting line: Jonathan Taylor 28.50 |
| WR | WR38Season rank WR38 through week 2, startable in a flex slot: Brian Thomas Jr. 6.90 | WR37Season rank WR37 through week 2, startable in a flex slot: Mike Evans 8.10 |
| WR | WR11Season rank WR11 through week 2, inside the league's starting line: Jaxon Smith-Njigba 14.30 | WR49Season rank WR49 through week 2, startable in a flex slot: DeVonta Smith 7.30 |
| WR | WR36Season rank WR36 through week 2, startable in a flex slot: Jerry Jeudy 7.10 | WR17Season rank WR17 through week 2, inside the league's starting line: Michael Pittman Jr. 6.00 |
| TE | TE1Season rank TE1 through week 2, No. 1 at the position: Tucker Kraft 21.40 | TE4Season rank TE4 through week 2, inside the league's starting line: Travis Kelce 8.10 |
| FLEX | RB16Season rank RB16 through week 2, inside the league's starting line: Alvin Kamara 13.00 | WR9Season rank WR9 through week 2, inside the league's starting line: Keenan Allen 14.60 |
| FLEX | WR33Season rank WR33 through week 2, startable in a flex slot: Chris Olave 8.40 | RB38Season rank RB38 through week 2, startable in a flex slot: Tyrone Tracy Jr. 7.10 |
| K | K1Season rank K1 through week 2, No. 1 at the position: Brandon Aubrey 23.00 | K4Season rank K4 through week 2, inside the league's starting line: Jake Elliott 12.00 |
| DEF | DEF6Season rank DEF6 through week 2, inside the league's starting line: HOU Defense 8.00 | DEF1Season rank DEF1 through week 2, No. 1 at the position: LAR Defense 9.00 |