| QB | QB1Season rank QB1 through week 6, No. 1 at the position: Patrick Mahomes 37.48 | QB3Season rank QB3 through week 6, inside the league's starting line: Baker Mayfield 23.64 |
| RB | RB35Season rank RB35 through week 6, startable in a flex slot: Rachaad White 16.10 | RB11Season rank RB11 through week 6, inside the league's starting line: Saquon Barkley 7.70 |
| RB | RB32Season rank RB32 through week 6, startable in a flex slot: Kareem Hunt 3.90 | RB4Season rank RB4 through week 6, inside the league's starting line: De'Von Achane 29.00 |
| WR | WR13Season rank WR13 through week 6, inside the league's starting line: Drake London 26.80 | WR18Season rank WR18 through week 6, inside the league's starting line: Zay Flowers 5.60 |
| WR | WR24Season rank WR24 through week 6, inside the league's starting line: Rashid Shaheed 4.80 | WR42Season rank WR42 through week 6, startable in a flex slot: DJ Moore 6.70 |
| WR | WR48Season rank WR48 through week 6, startable in a flex slot: Xavier Worthy 9.60 | WR70Season rank WR70 through week 6, outside the league's starting line: Sterling Shepard 6.10 |
| TE | TE3Season rank TE3 through week 6, inside the league's starting line: Jake Ferguson 10.80 | TE14Season rank TE14 through week 6, startable in a flex slot: David Njoku 4.30 |
| FLEX | WR47Season rank WR47 through week 6, startable in a flex slot: Matthew Golden 11.70 | RB19Season rank RB19 through week 6, inside the league's starting line: Kenneth Walker III 4.20 |
| FLEX | TE19Season rank TE19 through week 6, startable in a flex slot: AJ Barner 8.60 | RB63Season rank RB63 through week 6, outside the league's starting line: Hassan Haskins 2.80 |
| K | K4Season rank K4 through week 6, inside the league's starting line: Chase McLaughlin 6.00 | K7Season rank K7 through week 6, inside the league's starting line: Matt Prater 2.00 |
| DEF | DEF12Season rank DEF12 through week 6, outside the league's starting line: LV Defense 17.00 | DEF3Season rank DEF3 through week 6, inside the league's starting line: LAR Defense 19.00 |