| QB | QB2Season rank QB2 through week 1, inside the league's starting line: Josh Allen 39.66 | QB13Season rank QB13 through week 1, outside the league's starting line: Drake Maye 11.82 |
| RB | RB4Season rank RB4 through week 1, inside the league's starting line: Jahmyr Gibbs 31.10 | RB3Season rank RB3 through week 1, inside the league's starting line: D'Andre Swift 31.90 |
| RB | RB2Season rank RB2 through week 1, inside the league's starting line: Kenneth Walker III 32.60 | RB12Season rank RB12 through week 1, inside the league's starting line: Breece Hall 18.80 |
| WR | WR43Season rank WR43 through week 1, startable in a flex slot: Drake London 4.50 | WR4Season rank WR4 through week 1, inside the league's starting line: Amon-Ra St. Brown 23.70 |
| WR | WR14Season rank WR14 through week 1, inside the league's starting line: Mike Evans 13.90 | WR3Season rank WR3 through week 1, inside the league's starting line: Justin Jefferson 27.20 |
| WR | WR56Season rank WR56 through week 1, outside the league's starting line: Courtland Sutton 2.10 | WR30Season rank WR30 through week 1, inside the league's starting line: Luther Burden III 7.00 |
| TE | TE19Season rank TE19 through week 1, startable in a flex slot: Colston Loveland 0.00 | TE10Season rank TE10 through week 1, inside the league's starting line: Sam LaPorta 7.30 |
| FLEX | RB9Season rank RB9 through week 1, inside the league's starting line: Chuba Hubbard 22.20 | RB10Season rank RB10 through week 1, inside the league's starting line: Javonte Williams 21.70 |
| FLEX | RB6Season rank RB6 through week 1, inside the league's starting line: David Montgomery 27.40 | RB45Season rank RB45 through week 1, outside the league's starting line: Rico Dowdle 3.10 |
| K | K8Season rank K8 through week 1, inside the league's starting line: Cameron Dicker 2.00 | K9Season rank K9 through week 1, inside the league's starting line: Brandon Aubrey 1.00 |
| DEF | DEF3Season rank DEF3 through week 1, inside the league's starting line: SEA Defense 13.00 | DEF1Season rank DEF1 through week 1, No. 1 at the position: PIT Defense 20.00 |