| QB | QB11Season rank QB11 through week 1, outside the league's starting line: Joe Burrow 16.16 | QB14Season rank QB14 through week 1, outside the league's starting line: Baker Mayfield 11.64 |
| RB | RB8Season rank RB8 through week 1, inside the league's starting line: Jonathan Taylor 23.60 | RB27Season rank RB27 through week 1, startable in a flex slot: James Cook III 8.40 |
| RB | RB1Season rank RB1 through week 1, No. 1 at the position: Derrick Henry 34.80 | RB33Season rank RB33 through week 1, startable in a flex slot: Jadarian Price 6.80 |
| WR | WR28Season rank WR28 through week 1, inside the league's starting line: Tee Higgins 7.40 | WR16Season rank WR16 through week 1, inside the league's starting line: CeeDee Lamb 12.90 |
| WR | WR5Season rank WR5 through week 1, inside the league's starting line: Zay Flowers 23.50 | WR11Season rank WR11 through week 1, inside the league's starting line: Ladd McConkey 16.70 |
| WR | WR65Season rank WR65 through week 1, outside the league's starting line: Jordan Addison 0.00 | WR27Season rank WR27 through week 1, inside the league's starting line: Tetairoa McMillan 8.00 |
| TE | TE7Season rank TE7 through week 1, inside the league's starting line: Tyler Warren 8.80 | TE1Season rank TE1 through week 1, No. 1 at the position: Isaiah Likely 23.80 |
| FLEX | RB36Season rank RB36 through week 1, startable in a flex slot: Quinshon Judkins 6.00 | RB48Season rank RB48 through week 1, outside the league's starting line: Kenny Gainwell 2.30 |
| FLEX | RB5Season rank RB5 through week 1, inside the league's starting line: Ashton Jeanty 29.70 | WR33Season rank WR33 through week 1, startable in a flex slot: Jameson Williams 6.50 |
| K | K5Season rank K5 through week 1, inside the league's starting line: Ka'imi Fairbairn 9.00 | K2Season rank K2 through week 1, inside the league's starting line: Tyler Loop 14.00 |
| DEF | DEF2Season rank DEF2 through week 1, inside the league's starting line: JAX Defense 15.00 | DEF7Season rank DEF7 through week 1, inside the league's starting line: DEN Defense 3.00 |