| QB | QB1Season rank QB1 through week 2, No. 1 at the position: Josh Allen 46.82 | QB6Season rank QB6 through week 2, inside the league's starting line: Caleb Williams 7.72 |
| RB | RB2Season rank RB2 through week 2, inside the league's starting line: Jahmyr Gibbs 20.30 | RB25Season rank RB25 through week 2, startable in a flex slot: Travis Etienne Jr. 6.10 |
| RB | RB1Season rank RB1 through week 2, No. 1 at the position: Kenneth Walker III 20.80 | RB19Season rank RB19 through week 2, inside the league's starting line: Bhayshul Tuten 13.20 |
| WR | WR36Season rank WR36 through week 2, startable in a flex slot: Drake London 6.90 | WR12Season rank WR12 through week 2, inside the league's starting line: Ja'Marr Chase 23.00 |
| WR | WR16Season rank WR16 through week 2, inside the league's starting line: Mike Evans 6.90 | WR43Season rank WR43 through week 2, startable in a flex slot: DK Metcalf 4.70 |
| WR | WR54Season rank WR54 through week 2, outside the league's starting line: Courtland Sutton 4.00 | WR23Season rank WR23 through week 2, inside the league's starting line: DJ Moore -0.10 |
| TE | TE18Season rank TE18 through week 2, startable in a flex slot: Colston Loveland 0.80 | TE8Season rank TE8 through week 2, inside the league's starting line: Jake Ferguson 18.30 |
| FLEX | RB8Season rank RB8 through week 2, inside the league's starting line: Chuba Hubbard 13.40 | WR18Season rank WR18 through week 2, inside the league's starting line: Matthew Golden 7.80 |
| FLEX | RB10Season rank RB10 through week 2, inside the league's starting line: David Montgomery 3.40 | RB24Season rank RB24 through week 2, startable in a flex slot: Jacory Croskey-Merritt 5.30 |
| K | K9Season rank K9 through week 2, inside the league's starting line: Cairo Santos 4.00 | K2Season rank K2 through week 2, inside the league's starting line: Trey Smack 8.00 |
| DEF | DEF3Season rank DEF3 through week 2, inside the league's starting line: SEA Defense 8.00 | DEF7Season rank DEF7 through week 2, inside the league's starting line: SF Defense 9.00 |